ISOLATION AND ANTI-INFLAMMATORY EFFECT OF OSCILLATORIA ANNAE

Pallavi K. Vawhal* and Shailaja B. Jadhav

ABSTRACT

Oscillatoria is a genus of filamentous cyanobacteria which is named for the oscillation in its movement. Oscillatoria annae are a morphologically diverse group of oxygenic photosynthetic prokaryotes, which are phylogenetically closed related to each other and to chloroplasts. Oscillatoria annae widely useful in agriculture, bioremediation, clinical diagnosis, pharmacological aspect etc. It is very important organism for the health and growth of many plants. Many of these produce enzymes with unique properties. The present study was undertaken to assess anti-inflammatory activities of its ethanolic extract. Anti-inflammatory activity was evaluated by carrageenan induced paw edema. Ethanolic extract of Oscillatoria annae (EEOA) was studied for the anti-inflammatory activity by in vivo albino rat models. Diclofenac sodium was employed as reference drugs for anti-inflammatory studies. In the present study, the ethanolic extract of Oscillatoria annae (EEOA) demonstrated significant anti-inflammatory activities in the tested models.

Keywords: Oscillatoria annae, Ethanolic extract of Oscillatoria annae, Albino rats, Carrageenan, Paw edema.