A REVIEW ON MOUTH DISSOLVING FILMS

Quazi Bilal*, Shrikrushna Unhale, Snehal Shelke, Purva Kale, Prof. Rahul Sarode and Dr. K. R. Biyani

ABSTRACT

Oral route is considered as one of the most convenient route for administration of various pharmaceutical dosage forms like, tablet, capsule, syrup, suspension and emulsion. Fast Dissolving Drug Delivery systems have developed various fast disintegrating preparations like mouth dissolving film, MDT. Oral thin film are new dosage form that are prepared from hydrophilic polymer which are when placed in mouth, buccal cavity disintegrate rapidly. Mouth dissolving film is superior as compare to mouth dissolving tablet as the cost of production is low. Geriatric and pediatric patients are facing difficulty in swallowing of tablet and capsule, the oral film can bypass it, along with that it has other advantages like self-administrable, fast dissolving, rapid absorption that make it versatile dosage form. The aim of present study is to enlighten specifically different polymer along with their concentrations and applications. This study also focuses on use of plasticizer, polymer, sweetener, different methods which are used for the preparation of oral films and various evaluation parameter of the film.

Keywords: MDT:- Mouth Dissolving Tablet, oral films, pediatric patients, evaluation, Buccal cavity, dosage forms, Tensile strength.