SINGLE-INHALER TRIPLE THERAPY FOR COPD EXACERBATION

Jisna Babu, *Juby Bensen and Dr. Akhila S. Arjun

ABSTRACT

Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease that includes chronic bronchitis and emphysema and is characterized by airflow limitation. Triple inhaled therapy consists of inhaled corticosteroids (ICSs), long-acting β2-agonists (LABAs), and long-acting muscarinic receptor antagonists (LAMAs) has been recommended for COPD patients who still have clinically significant symptoms following the use of a dual inhaler with LABA plus LAMA or LABA plus ICS and those who have a higher risk of exacerbation. Studies have shown that triple inhaled therapy has positive effects on lung function and COPD symptoms as compared with dual therapy. This review concludes that triple inhaled therapy is more effective than dual therapy for COPD patients.

Keywords: Chronic Obstructive Pulmonary Disease, Inhaled corticosteroid, Long-acting ?2-agonists, Long-acting muscarinic receptor antagonists.