DESIGN AND SYNTHESIS OF A NOVEL PYRAZOLO[3,4-B]QUINOLINYL ACETOHYDRAZIDE AND SCHIFF BASE DERIVATIVES

Nader M. Mahmoud*, Farag A. El-Essawy and Eman Farouk

ABSTRACT

A novel series of pyrazolo[3,4-b]quinolinyl acetohydrazide and Schiff base derivatives were prepared via various regents started from the key-intermediate 2-(6-methyl-1H-pyrazolo[3,4-b]quinolin-1-yl)acetohydrazide 9. most of the novel-prepared compounds have been elucidated using spectroscopic analyses (NMR, and EI-MS).

Keywords: Pyrazolo[3,4-b]quinolone, Quninoline, pyrazolo, Schiff base, Synthesis.