EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

RP-HPLC METHOD FOR THE SIMULTANEOUS DETERMINATION OF RELATED COMPOUNDS OF OCTREOTIDE ACETATE DEPOT SUSPENSION (MICROSPHERES)

Jerripothula Ganesh* and Bandi Veera Babu*

ABSTRACT

The analysis of Octreotide Acetate and related compounds Depot Suspension (Microspheres) By using RP-HPLC method using columm Waters X-Bridge C18 (250 X 4.6 )mm, 5μm with Flow rate 1.0 mL/min, Injection volume 50 μL, Wavelength 210 nm, Run time 70 minutes, Elution using Gradient programm, the Rt for Octreotide was found to be 28.23, related compunds like N- Acetyl Octreotide was found to be 24.32 Des Threoninol Octreotide was found to be 34.24. The suitable was developed for the indetification of the related compounds present in the Octreotide Acetate formulation.

Keywords: Octreotide Acetate, N-Acetyl Octreotide, Des Threoninol Octreotide, RP-HPLC, Microspheres, Depot Suspension.

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SJIF Impact Factor: 7.065

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Its Our pleasure to inform you that, EJPMR 1 May 2025 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

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EUROPEAN JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH