ANTIBACTERIAL ACTIVITY OF CASSIA AURICULATA AND EUGINEA JAMBOLANA AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS

R. Kanchana, Dr. B. Bharathi* and Dr. Deepa C. Philip

ABSTRACT

Background: Various medicinal properties have been attributed to natural herbs. The antibiotic resistant microorganisms has increased in past three decades. The Methicillin Resistant Staphylococcus aureus(MRSA) is a problematic pathogen in the field of medical science. This organism tends to cause serious infection in the burn patients and causing higher mortality. Thereby our study aims to control these micro-organisms using various plants extracts. Natural products of higher plant may possess a new source of antimicrobial agent with possible novel mechanism of action. Aim: The main objective of this study is to evaluate the antibacterial activity of E.jambolana and C.auriculata against MRSA and to do screening for phytochemical constituents. Materials and methods: A prospective study was conducted to analyse the phytochemical components and to compare the efficacy of ethanolic, ethylacetate, diethyl ether, hexane and aqueous extracts of E.jambolana and C.auriculata on MRSA. Results: The highest inhibition zone 20mm was observed in 45 μl ethylacetate and aqueous extracts of C.auriculata and 18mm highest zone was observed in 45μl ethylacetate extracts of E.jambolana. Conclusion: The inhibitory effect of the extracts justified the medicinal use of both plants Cassia auriculata and Eugenia jambolana. In future after the detailed study these medicinal plants can be used as potent biochemical drugs to overcome the infections caused by these organisms.

Keywords: Methicillin Resistant Staphylococcus aureus, Eugenia jambolana and Cassia auriculata.