EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EVALUATION OF ANTIDIABETIC ACTIVITY OF SWERTIA CHIRAYITA AND PANAX GINSENG

*Samreen Begum, Dr. A. Srinivasa Rao and M. Sri Ramachandra

ABSTRACT

Diabetes mellitus, one of the most common endocrine disorders has caused significant morbidity and mortality due to macro vascular and micro vascular complications. Currently available therapies for diabetes include insulin and various oral anti diabetic drugs have number of serious adverse effect; therefore the search for more effective and safer hypoglycemic agents is one of the important areas of investigation. Some medicinal plants have been reported to be useful in diabetes worldwide. The herbs like swertia chirayata shown to protect the liver. It contains xanthones which is reputedly effective against Malaria, Tuberculosis. It also cures constipation and used for treating dyspepsia with all other properties the swertia chirayita shows good anti diabetic activity. The other herb which was used to carry out the experiment panax ginseng is well effective in case of anti-sterility in men, it prevents cancer and fight chemical dependency (anti proliferative). The study was conducted to examine the possible antidiabetic activity of swertia chirayata and panax ginseng leaf extraction on male wistar rats. Gold thio glucose method was used to induce diabetes in rats. Initially blood glucose levels were increased abruptly after induction. After giving the oral administration of ethanolic extract of swertia chirayat (100mg/ Kg, 200mg/kg) and panax gingseng (250mg/kg, 100mg/kg). Finding of this research showed that ethanolic extract of a plant swertia possess phytochemicals like steroids, alkaloids, tannins, flavonoids and panax ginseng possess alkaloids, carbohydrates, flavonoids and tannins significant (P< 0.05) anti diabetic activity. The results were compared with standard drug metformin (400mg/kg).

Keywords: Swertia chirayita, panax ginseng, Antidiabetics.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 September 2020 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR SEPTEMBER ISSUE PUBLISHED

    SEPTEMBER 2020 Issue has been successfully launched on 1 September 2020.

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing