EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

A PATHOLOGICAL STUDY OF GASTRIC OUTLET OBSTRUCTION

*Dr. C. Rajmohan, MS and Dr. Selladurai

ABSTRACT

Introduction: Gastric outlet obstruction is due to obstruction in first part of duodenum at the site of chronic scarring from ulceration or antrum where a benign gastric ulcer (type II and type III) or carcinoma is a problem. Stenotic complications of peptic ulcer disease are hour glass deformity and tea pot deformity (gastric ulcer). Stenotic complications arise from repeated cycles of ulceration and healing resulting in dense fibrosis with narrowing and deformity. Common causes of gastric outlet obstruction are Chronic duodenal ulceration / fibrosis, Antral gastric carcinoma, Carcinoma of the head of pancreas. Aim of The Study: To evaluate the age and sex incidence of gastric outlet obstruction. Also Pathological study on causes of gastric outlet obstruction and to correlate the results of upper gastrointestinal endoscopy, biopsy and peroperative findings in gastric outlet obstruction. Materials and Methods: This was a pathological study on gastric outlet obstruction comprising of 34 cases of gastric outlet obstruction. The patients have been selected from Tirunelveli Medical College Hospital in the Surgery department from December 2010 to December 2011. The cases were selected with following inclusion and exclusion criteria. An elaborate study of all the patients with regard to history, clinical features, routine investigations, endoscopy and biopsy report, pre operative management, per-operative findings, post operative management and complications during post operative period is managed. Patient general condition, nutrition status, hydration and co-morbid conditions were managed before surgery. Results: Gastric outlet obstruction is common in age less than 50 years is 14 (40%). In 10 patients it is due to malignancy and in 4 patients it is due to benign lesion. In age between 50 to 55 years 8 pateints (24%) develop gastric outlet obstruction. In 7 patients the cause is malignant lesion and in one patient the cause is cicatrized duodenal ulcer in 1st part of duodenum. In age between 56 to 60 years 4 patients had gastric outlet obstruction and in all 4 patients cause was malignant lesion. In age between 61 to 65 years 5 patients had gastric outlet obstruction. In 3 patients the cause is malignant lesion and in 2 patients it was due to benign lesion. In age above 65 years 3 patients develop gastric outlet obstruction and the cause is malignant lesion. In this study young age to develop gastric outlet obstruction is 30 years due to cicatrized duodenal ulcer and oldest age is 75 years due to gastric carcinoma. The age incidence is 30 to 75 years with mean of 52.5 years. The young age to develop gastric carcinoma is 35 years. Conclusion: The present study is a pathological study on gastric outlet obstruction. The observations from the data and results obtained in the present study were Male patients are more commonly affected by gastric outlet obstruction. Carcinoma in pyloric antral region was the most common cause of gastric outlet obstruction. Vomiting and dehydration are the common symptoms and signs of gastric outlet obstruction. Upper gastro intestinal endoscopy and biopsy are the Gold standard investigation for gastric outlet obstruction. It has been used for both diagnostic purpose and taking biopsy from the lesion. All patients above 40 years with symptoms of dyspepsia should undergo upper gastro intestinal endoscopy and biopsy examination.

Keywords: .


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing