EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

PRELIMINARY PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF HYGROPHILA SCHULLI

Manisha U. Mishra*, Nitin H. Indurwade, Shubham R. Ukey, Rahul Chaurasia, Sanket S. Murmurwar

ABSTRACT

Hygrophila Schulliis an important plant described in Indian Ayurvedic literature. The main objective of the present study was to carry out preliminary phytochemical screening and evaluation of antibacterial activity of H.schulli collected from local areas of Gondia city, Maharashtra State, India. The plant material was identified and fresh leaves were collected. The dried leaf powder was extracted by hydro-alcoholic solvent extraction method using Soxhlet apparatus. The extract was qualitatively analyzed for presence of active phytochemicals prior to study of the antibacterial activity and minimum inhibitory concentration. The extracts containing different concentrations of H.schulli were investigated against clinically effective bacterial pathogens such as Staphylococcus aureus, Bacillus subtilis and Escheria coli. Streptomycin powder was used as a standard drug for analyzing antibacterial activity. The highest inhibition zone of 20 mm was observed against Bacillus subtilis with plant extract in the concentration of 100μg/ml. The results revealed that the hydroalcoholic extract of H.schulli possesses antibacterial potential as reported in earlier investigations and have the potential in the treatment of bacterial infections. Further the studies were extended to formulate a cream containing hydroalcoholic extract of H.schulli for topical application and its evaluation. It was found that the hydroalcoholic extract of H.schulli can be formulated as cream and used for topical application.

Keywords: Hygrophilliaschulli, Hydroalcoholic extraction, Leaf extract, Antibacterial activity, Minimum inhibitory concentration, Cream formulation.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing