ANTIMICROBIAL ACTIVITY OF PAEDERIA FOETIDA.L AGAINST ENTEROPATHOGENS
*Dr. Paramita Gangopadhyay Bhattacharya, Ankita Guha Barman, Dr. Amit Chakravarty and Deepanwita Dey
Ayurvedic medicine Kolthee churna, known to be effective in diarrhoea diseases. Paederia foetida L. commonly known as the Gandal patta. The antibacterial activities of n-hexane, chloroform, ethyl acetate fractions of methanolic extracts of the whole plants Paederia foetida L. (family Rubiaceae) were screened against various pathogenic bacteria such as Bacillus cereus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Shigella sp. Vibrio cholereae, by „agar cup plate method‟. The Ethanol extract of the whole plant possesses antimicrobial activity but the n-hexane fractions exhibited moderate to less activity against some organisms tested compared with the standard antibiotic Metronidazole. The ethanol and the hexane extract showed highest antibacterial activity against Salmonella typhi, Vibrio cholerae, Moderate antibacterial activity against, Enterobacter sp, E.coli. lowest antibacterial activity against Enterococcus sp., Bacillus substilis.
Keywords: Paederia foetida, Antimicrobial activity, Methanol extractive Enterobacter sp.
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