EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

PREVALENCE AND ASSESSMENT OF ANTIBIOTIC SUSCEPTIBILITY PROFILES OF COAGULASE-NEGATIVE STAPHYLOCOCCI ISOLATED FROM CLINICAL SAMPLES.

*Olajubu, F. A. and Deji-Agboola, A. M

ABSTRACT

Background: Persistent increase in Microorganisms’ resistance to available antibiotics has become a global concern. The changing role of many microorganism from non-pathogenic normal body flora to pathogenic strains increases the need for regular surveillance of antibiogram profile of clinical isolates. This study was designed to investigate the prevalence and susceptibility pattern of Coagulase-Negative Staphylococci (CoNS) in Sagamu area of Ogun State, Nigeria. Materials and Methods: This 5-year retrospective study covered between 2011 and 2015 with 115 coagulase negative staphylococci isolated. The isolation, identification, assessment for methicillin resistance and susceptibility testing of the isolates followed the standard methods of Clinical Laboratory Standard Institute (CLSI). Results: CoNS were isolated from 72 females and 43 male patients with 30.4% isolated from Urine samples. The highest number of CoNS (34) was isolated in 2014 while the lowest (14) in 2012. Seventy-three (63.5%) of the CoNS isolates were screened methicillin resistant (MRCoNS). All the MRCoNS were resistant to Penicillin, 84.9% to Cephalexin and 28.8% to Gentamycin. No resistance against Ciprofloxacin among MSCoNS but 71.2% among MRCoNS. Multidrug resistance was observed among the two groups of CoNS. Conclusion: The importance of continous monitoring of the antibiogram of CoNS cannot be overemphasized. This study will provide the needed guide for clinicians in antibiotic selection and formulation of antibiotic policy to curb spread of resistant strains.

Keywords: Coagulase-Negative Staphylococci (CoNS), Sagamu, Retrospective study, Methicillin Resistance CoNS, MSCoNS.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )