EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

DIAGNOSTIC VALUE OF SYNOVIAL BIOPSY IN A TUNISIAN INSTITUTION: ABOUT 43 CASES

*Dr. Faten Limaiem and Saadia Bouraoui

ABSTRACT

Introduction: histopathological study of synovial biopsy is one of the most valuable means for the diagnosis of joint diseases, as clinical diagnosis has its own limitations. Aim: to evaluate the reliability of the synovial biopsy in the etiological diagnosis of mono- and oligo-arthropathies. Methods: our retrospective study concerned 43 synovial biopsies collected at the department of pathology of the university hospital Mongi Slim La Marsa hospital over a three-year period (March 2015- March 2018). Results: the average age of our patients was 56.18 years with extremes ranging from 24 to 80 years old. In our series, synovial biopsies were performed exclusively in large joints. They interested in order of frequency the knee (79%), the hip (9%), the elbow (7%) and the ankle (5%). Histopathological examination classified synovial biopsies into septic arthritis (n=23), mechanical arthropathy (n=5), rheumatic synovitis (n=5), reactive synovitis (n =7), chondrocalcinosis (n=1) and metastatic adenocarcinoma of synovium (n=1). The definitive diagnosis was based on a set of arguments including clinical, biology, radiological examination, histology and evolution data. The pathological examination was consistent with the suspected clinical diagnosis in 90% of the cases. Conclusion: Synovial biopsy is an important and final tool for definitive diagnosis of joint disorders. Correlation with clinical, radiological, and serological findings helps to arrive at an accurate diagnosis.

Keywords: Synovial, biopsy, arthritis, synovitis, pathology.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing