EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF PHYTOMEDECINE MATHESIA, A DRUG USE AGAINST BURULI ULCER IN REPUBLIC DEMOCRATIC OF THE CONGO (DRC)

Helmont Nkasa Liwata, Clément Inkoto Liyongo*, Jean Claude Muzomwe Mayaliwa, Edith Masengo Ilunga, Caleb Muzomwe Mumba, Christophe Mulenga Mbombo and Taba Kalulu Muzele

ABSTRACT

Buruli ulcer is a debilitating skin disease caused by Mycobacterium ulcerans. In recent years, the disease has become an important public health problem in an increasing number of tropical and subtropical countries. In this study the aims was to determine the phytochemical composition and to assess the antibacterial activity of Phytomedecine Mathesia. This study has place and duration in Faculty of Science, University of Kinshasa, between November 2012 and April 2013. The antibacterial activity of Mathesia extract was assessed using disc diffusion and micro-dilution methods respectively. The disc diffusion method was used to determine the antibacterial activity of extract while the micro-dilution method was performed to determine their Minimal Inhibitory Concentration. This study revealed presence of alkaloids reducing sugars, steroids, terpenes and total polyphenols like tannins, flavonoids and saponins in Mathesia extract. The results of this study revealed that extract of Mathesia possesses antibacterial activity. This study provides a scientific basis for the antibacterial activity of Mathesia extract. Isolation and purification of different phytochemicals may further yield significant antibacterial new leads compounds.

Keywords: Phytomedecine Mathesia, Phytochemical and Antibacterial activity.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing