EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

LUBANOID - A NEW NATURAL TOPICAL FOR ANAL FISSURE

Dr. Luay Rashan, Dr. Mohammed Rishan and Dr. Rafie Hamidpour*

ABSTRACT

An anal fissure is a small tear in the thin, moist tissue (mucosa) that lines the anus. An anal fissure may occur when you pass hard or large stools during a bowel movement or frequent diarrhea can also tear the skin around the anus. Anal fissures typically cause pain and bleeding with bowel movements. You also may experience spasms in the ring of muscle at the end of the anus. Anal fissures are very common in young infants but can affect people of any age and it is often seen in infants and young children since constipation is a common problem in these age groups. Other common causes include; straining during childbirth or bowel movements, inflammatory bowel disease, such as Crohn’s disease, decreased blood flow to the anorectal area overly tight or spastic anal sphincter muscles. In rare cases, an anal fissure may develop due to anal cancer, HIV, tuberculosis, syphilis and herpes. Anal fissures affect males and females equally; however, an anterior fissure is more likely to develop in women (25%) than in men (8%). Although anal fissures are the most common cause of rectal bleeding in infants, they are primarily seen in young adults. Eighty-seven percent of people with a chronic anal fissure are between the ages of 20 and 60 years. The incidence of anal fissure is around 1 in 350 adults. Anal fissures in children may indicate sexual abuse. Most anal fissures get better with simple treatments, such as increased fiber intake or sit baths. Some people with anal fissures may need medication or, occasionally, surgery. Lubanoid is an herbal-based evidence topical product formulated from six natural, safe and monographic herbal ingredients, which is designed specifically as a remedy for anal fissures, foot fissures, piles and inflamed veins such as varicose and spider veins. Studies conducted in vitro, in vivo and clinically showed that Lubanoid is a novel synergistic composition with potential anti-inflammatory, analgesic and healing effects and found superior in its activity compared with some drugs used currently in the clinics.

Keywords: .


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing