A CASE REPORT ON HYPERSENSITIVITY REACTION WITH METFORMIN
Rohit Bangwal* and Nadeem
ABSTRACT
Metformin is a biguanide derivative widely used for treatment of diabetic patients. The most common toxic effects of metformin are gastrointestinal (anorexia, nausea, vomiting, abdominal discomfort and diarrhoea). As with other drugs, allergic reactions can occur with metformin also, but these are very rare. A case of hypersensitivity reaction with metformin was reported in adverse drug monitoring centre. A 56-year-old female, newly diagnosed case of Type-2 diabetes mellitus, started on Tablet Metformin 500 mg twice daily, now few days after starting the drug (tablet metformin 500 mg) developed purpuric and skin rashes lesions on her legs, arms and back. Physician was immediately stopped the metformin and patient was put on tablet glimepiride 2 mg. The lesions slowly started subsiding after stopping metformin.
Keywords: Metformin, Skin lesions, Hypersensitivity reaction, Glimepiride.
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