EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

CHEMICAL CONSTITUENTS FROM THE RHIZOMES OF ACORUS CALAMUS, AERIAL PARTS OF DIGERA MURICATA, FRUITS OF GREWIA ASIATICA AND LEAVES OF OCIMUM SANCTUM

Shahnaz Sultana, Mohammed Ali*, Showkat Rassol Mir and Shazia Usmani

ABSTRACT

The rhizomes of Acorus calamus L. (Acoraceae), aerial parts of Digera muricata (L.) Mart. (Amaranthaceae), fruits of Grewia asiatica L. (Malvaceae) and leaves of Ocimum sanctum L. (Lamiaceae) are used to treat various diseases. This study was planned to isolate phytoconstituents from these plant materials and to characterize their structures. The air-dried powders of the herbal drugs (1.0 kg each) were exhaustively extracted with methanol individually and the concentrated each extract was adsorbed on silica gel separately for preparation of slurries. Each dried slurry was subjected to silica gel column packed in petroleum ether. The columns were eluted with organic solvents in order of increasing polarity to isolate the compounds. The rhizomes of A. calamus afforded stearyl oleate (1) and eudesman-11-ol-8β, 13-olide (2). The aerial parts of D. muricata furnished phenolic glucosides identified as 3-isopropanoic acid phenyl 1-O-α-D-glucopyranoside (3) and resorcinyl 1-O-β-D-glucopyranosyl-(6′→1′′)-O- β-D-glucopyranoside (4). An acyclic sesquiterpenic acid 2,10-dimethyl-6-methylene dodecan-1-oic acid (5) and cerotic acid (6) were isolated from the fruits of Grewia asiatica. The leaves of O. sanctum gave a carotenol carot-4,6,8,10,12,14,2′(17′), 6′(8′), 10′(19′),14′(20′)-decaene-1′-ol (ocimum xanthin, 7) and a diterpenic ester kaur-5,15(17)-dien-7β-olyl vanillate (kaurdienoyl vanillate, 8). The structures of these phytoconstituents have been established on the basis of spectral data analysis and chemical reactions.

Keywords: Acorus calamus rhizomes, Digera muricata aerial parts, Grewia asiatica fruits, Ocimum sanctum leaves, phytoconstituents, isolation, characterization.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • EJPMR: JANUARY ISSUE PUBLISHED

    JANUARY issue has been successfully launched on 1 JANUARY 2023.

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 January 2023 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database