EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

ACUTE TOXICITY STUDIES OF EDIBLE OIL EXTRACTED FROM INDIGENOUS SEEDS

Kiran A. Suryavanshi*, Dr. Yogesh V. Ushir and Dr. Venkat Chellam

ABSTRACT

Now a days ayurvedic dosage forms are preferred over allopathic. So for the safer use these plants and its preparations need to be evaluated for their toxicity. The main aim of this study was to test the acute toxicity of natural oils extracted from indigenously edible such as Buchanania lanzan spreng. belonging to family Anacardiaceae, commonly known as Chironji in Hindi, Buchanania lanzan spreng is a tree of 12-15 mt high, with straight trunk, and Simmondsia chinesis., belonging to family from Simmondsiacea commonly known as Jojoba in Hindi is a large, evergreen, forest tree more than 30 mt in height a tree. These two plants are easily available and their various parts are used in treatment of various diseases traditionally. The acute toxicity study was studied on Swiss mice with a dose of 2 g/Kg body weight orally. The single administration exposure of the seed oil on Swiss mice was carried out and the exposure route was oral with water as a vehicle. The observations of changes in body weight, food and water intake as well as cage side observations were reported. The plants were found to be nontoxic as no mortality was recorded even at the highest dose level.

Keywords: Ayurvedic, Toxicity, Natural oil.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia