( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



*Orugbo V. P.


Introduction: Screening for diabetic nephropathy (DN) facilitates early detection, evaluation, and treatment. A spot urine sample used to measure the albumin to creatinine ratio (ACR) accurately reflect the total 24 hour level of urine albumin excretion and the ACR is now recommended by the American Kidney Foundation as the screening tool for patients with diabetes. There are however many drawbacks to the cut off value of 30mg/g. Thus this study aimed to assess the diagnostic accuracy of spot Urinary albumin-to-creatinine ratio in diabetic nephropathy based on the cut off value of 30mg/g. Method: A hospital based cross sectional study involving 80 DN cases being managed in the University of Benin Teaching Hospital. The controls were 80 non diabetic persons from the University of Benin Teaching Hospital. The cases were selected using systematic sampling method and data collected using structured questionnaire after obtaining informed consent. They were sampled for Serum Creatinine, Serum Urea, Urinary Albumin and Creatinine. Urinary albumin-to- creatinine ratio and creatinine based glomerular filtration rate were calculated from the results. Data was analyzed using IBM SPSS version 25 and presented in form of tables, charts and graphs. Results: Of the total of 160 patients, 80 were DN cases and 80 were non diabetic controls. The study showed a significant difference between the mean levels of serum creatinine and urea, urinary creatinine and albumin, urinary albumin –to- creatinine ratio, and eGFR between the cases and controls. The diagnostic accuracy of UACR was higher with cut off value 57.8182mg/g. Conclusion: Serum UACR was shown to have a higher diagnostic accuracy in diagnosing diabetic nephropathy at 57.8182mg/g compared to 30mg/g.

Keywords: Urinary Albumin-to-Creatinine Ratio(UACR), Diabetic Nephropathy(DN), Estimated Glomerular Filtration Rate(eGFR), Urinary Albumin, Urinary Creatinine.

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database