APPLICATION OF FIBRINOLYTIC ENZYME FROM ASPERGILLUS TAMARII – INVITRO STUDIES
Shilpa H. K.*, Jeevan G. Ambekar1, Nilima N. Dongre and Dr. Siddalingeshwara K. G.
Fibrinolysis is the process in which fibrin clots are broken down to soluble products (Casarman-Maus and Hajjar,
2005). The main enzyme responsible for fibrinolysis is plasmin which cuts the fibrin mesh and converts it to
soluble form which will be cleared from the body by kidney and liver. Fibrinolytic enzyme production were
studied in the filamentous fungi Aspergillus tamarii SAS 02 a soil isolate from different regions of Karnataka. The
enzyme tested for fibrinolytic activity for in-vitro studies by clot hydrolysis in capillary tube with standard enzyme
which are available in market.
Keywords: Fibrinolytic enzyme, Fibrin, blood clot, in vitro study and submerged fermentation.
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