EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

STUDY ON DRUG UTILIZATION PATTERN OF NON-STEROIDAL ANTI-INFLAMMATORTY AGENTS IN GERIATRIC PATIENTS AT A TERTIARY CARE TEACHING HOSPITAL

Dr. B. Chitra*, Juble Raju, Juby Liz Jacob and J. Marie Cathrine

ABSTRACT

Increased use of NSAIDs in geriatrics has expressed great concerns as these drugs have the potential to cause gastrointestinal, renal and cardiovascular adverse effects. The present study aims to evaluate the prescribing pattern of NSAIDs, analyze the rationality of prescriptions using Beers criteria 2015 and to identify the drug interactions in prescriptions using micromedex drug database. The current study was a prospective observational study which was performed in 160 patients. Geriatric patients above the age of 60 prescribed with atleast one NSAID and those willing to participate were included in the study. Potential inappropriateness was identified in 51(31.84%) prescriptions. Among the drugs prescribed to the study population diclofenac, aspirin, indomethacin, ketorolac and ibuprofen were found to be inappropriate in geriatrics as per beers criteria 2015. The study also reports that 60% of the prescriptions had drug interactions. The drugs were administered via oral, intravenous, intramuscular and topical routes. Intravenous administration (52.68%) was the most common route observed in the present study. Appropriate use of NSAIDS reduces the severity of adverse effects and thus helps in improving the quality of life in geriatric population. Knowledge on the prescribing pattern, rational use and risk factors associated with use of NSAIDS in geriatric population will help the healthcare professional to ensure safer and better treatment outcomes.

Keywords: Geriatrics, Non - steroidal anti-inflammatorty agents, Beers criteria, Gastro-intestinal toxicity.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )