EVALUATION OF ANTI INFLAMMATORY AND ANALGESIC ACTIVITIES OF THE EXTRACT PREPARED FROM ALOYSIA POLYSTACHYA IN EXPERIMENTAL ANIM ALS
Sara Parveen*, M. Sri Ramachandra and Dr. A. Srinivasa Rao
Aloysia polystachya used as an appetite suppressant herb for millennia. It also has antioxidant, ant diabetic, and nootropic actions. It is proved that it is a natural anti obesogenic agent and is widely consumed in India. Its actions like anti-atherosclerotic is of high medicinal value. The phytochemical screening of extract shows the presence of alkaloids, phytosterols, phenolic compunds and tannins using various methods. In the present work an attempt has been made to evaluate the anti inflammatory, analgesic activities of ethanolic extract of aloysia polystachya (100mg/kg, 200mg/kg) and the results were found to be positive. The results were compared with the standard drug indomethacin (10mg/kg), pentazocin (10mg/kg) and aspirin (10mg/kg). Hence, aloysia polystachya contains anti inflammatory and analgesic activity. The present work was done to demonstrate the anti inflammatory and analgesic activity of the ethnolic extract obtained from the leaves of aloysia polystachya (verbenaceae). Inflammation was induced by carrageenan induced paw edema and pain was induced by eddy’s hot plate and tail flick method. Thermal and radiant heat is used in hot plate and tail flick method respectively.
Keywords: Aloysia polystachya, analgesic, anti inflammatory activity.
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