EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

EFFECT OF SERUM CORTISOL AND PROLACTIN ON DIABETIC RETINOPATHY

Dr. Khan S.*, Sabah S., Waris A., Siddiqi S. S.

ABSTRACT

Diabetes mellitus[DM] is a group of metabolic disorders with various complications that include Nephropathy, Neuropathy and Retinopathy. Diabetic retinopathy refers to retinal changes seen in patients with diabetes mellitus which may lead to marked disability. Eye changes in Diabetes may lead to various hormonal changes and vice versa hormonal changes may increase the progression of diabetic retinopathy. Degree of cortisol secretion is related to the presence and number of diabetic complications (Diabetes care 30:83-88, 2007). The hormone prolactin is proteolytically processed to vasoinhibins, a family of peptides that inhibit the excessive retinal vasopermeability related to diabetic retinopathy after its intraocular conversion to vasoinhibins (Diabetes 59:3192-3197, 2010). The Research aims to find out whether serum cortisol and prolactin levels in patients could lead to progression of diabetic retinopathy.

Keywords: Diabetic Retinopathy, Cortisol, Prolactin, Microvascular complications.

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