EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

ANTIBACTERIAL EFFICACY OF HERBAL EXTRACTS & ESSENTIAL OILS FROM TRADITIONAL MEDICINAL PLANTS AGAINST BACTEROIDES FRAGILIS GROUP ISOLATED FROM CLINICAL SPECIMEN

Zomuanpuii Colney, Beena Antony*, Ramesh Kulkarni

 

ABSTRACT

Introduction: B fragilis group is one of the most frequently isolated anaerobic pathogens with the highest antibiotic resistance. They also exist as normal flora in the human gut and female genital tract. Due to empirical treatment and lack of monitoring, the incidence of drug resistant strains has increased and treatment has become challenging. The emergence of these resistant strains has created the demand for alternative drugs. Aim and objectives: To evaluate the antimicrobial efficacy of various medicinal herbal extracts against B fragilis group. Materials and Methods: A total of 58 strains of B fragilis group were isolated from various clinical samples and identified according to standard procedures. The essential oils from medicinal plants were extracted using Neo-Clevenger apparatus and alcohol extracts by Soxhlet apparatus. Screening of the antimicrobial activity of herbal products was performed by employing disc diffusion technique. Minimum inhibitory concentration was determined by agar dilution method. Results: Essential oils (lemongrass, cinnamon, nutmeg, clove bud, ginger, garlic) and Kokum extract (aqueous and alcohol) were tested for their antibacterial efficacy. Essential oils of Cinnamon, clove and lemongrass were very active to these organisms with a percentage of 98.2%, 96.5%, 89.6% respectively. The MIC ranges from 5μg/ml to 0.156μg/ml for cinnamon oil. Conclusion: The present study has demonstrated that herbal products exhibit good in vitro antimicrobial action against B fragilis group. The results suggest that they have high potential to open new avenues in the development of alternate therapeutic options.

Keywords: B fragilis group, antimicrobial susceptibility testing, essential oils, herbal extract.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 December 2021 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR: DECEMBER ISSUE PUBLISHED

    DECEMBER Issue has been successfully launched on 1 December 2021.

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )