EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

OUR EXPERIENCE USING DIFFERENT BARICITIES OF BUPIVACAINE FOR UNILATERAL SUBARACHNOID BLOCK ANESTHESIA IN DIFFERENT LOWER LIMB ORTHOPEDIC SURGICAL PROCEDURES

Luai K.Aldaklalah MD.*, Mutaz L. Ghabashneh MD., Mohammad Ali Alsuqour MD., Nizar A. A. Abualannaz MD, Mahdi S. A. Jaradat MD.

 

ABSTRACT

Background: Unilateral subarachnoid block anesthesia uses decreased dosage, low speed of administration and lateral positioning to enhance unilateral drug distribution. Aim: To assess the effect of various baricities of bupivacaine solutions during unilateral subarachnoid block anesthesia in patients scheduled for various lower limb orthopedic surgical techniques. Methods: This prospective, double blind and randomized investigation included 122 patients, of both sexes, aged 33-71 yrs, classed II-III by the American society of Anesthesiologists and assigned for various lower limb orthopedic surgical techniques under unilateral subarachnoid block anesthesia at Prince Rashid military hospital, Irbid, JORDAN, during the year 2016.Patients were grouped in a random fashion into 2 groups. Group I patients were administered subarachnoid 10 mg of 0.5% isobaric bupivacaine solution (2 ml) (Group I, n=61)) or subarachnoid 10 mg of 0.5% hyperbaric bupivacaine solution (2 ml) (Group II, n=61), both in the L3-4 interspace with the patient in the lateral position and keeping such for 15 minutes. Sensory anesthesia was assessed by the pin prick test. Motor blockade was assessed by the Bromage score. Both blockades were compared with the contralateral side. Statistics: Mean age, height and length of the blockade were evaluated by Analysis of Variance, while the level of the sensory and motor blockades was evaluated by the Mood test for medians. The unilaterality of the anesthesia was evaluated by the Chi-square test. P-value less than 0.05 was considered statistically. Results: There was a significant discrepancy between the side of the surgery and the contralateral side in the two groups at 15 minutes, but the incidence of unilateral subarachnoid block anesthesia was more with the hyperbaric solution. Sensory and motor blockades were recorded in 18 patients (29.5%) in group I and in 48 patients (78.7%) in group II (P<0.05). Conclusions: Subarachnoid block anesthesia with hyperbaric bupivacaine solution has significantly more incidence of unilateral subarachnoid block anesthesia than isobaric bupivacaine solution after 15 minutes.

Keywords: Bupivacaine; unilateral subarachnoid block anesthesia; lower limb orthopedic surgery; blockade: sensory, motor.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )