EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

ZINC PEROXIDE NANOPARTICLES: PROMISING SOURCE COMBATING CHICKEN MEAT-CONTAINING PATHOGENS

Esraa A. Abdelkrim*, Mohamed A. Hussein and Abd-Elsalam E. Hafez

ABSTRACT

Due to the increase of the chicken meat consumption, the ensuring of microbial safety is essential. Therefore, our study aims to assess the microbiological quality of retailed chickens in local markets at El-Sharkia Governorate, Egypt. Besides, investigating zinc peroxide nanoparticles (ZnO2-NPs) antibacterial activity against pan drug-resistant bacteria (PDR). For this purpose, an Antibiotic susceptibility test was performed using 10 different antibiotics to detect MDR and PDR bacteria in retail chicken meat cuts-up. All PDR bacteria were selected and identified using 16S rRNA. Also, the activity of ZnO2-NPs was investigated against PDR isolates. Our results showed that the average total viable count (TVC) of fresh, chilled and frozen meat estimated by 6.84, 3.75 and 2.1 log10 CFU/g, respectively. The antibacterial susceptibility test revealed that 70% (84/124) of all bacterial isolates were MDR bacteria. Out of these isolates 5 PDR isolates were detected and identified as Pseudomonas aeruginosa IMD85, Escherichia coli O157:H7 and Salmonella enterica ATCC 8387, Staphylococcus aureus 191 and Staphylococcus epidermidis BGHMC11. The antibacterial susceptibility test of ZnO2.NPs against these PDR isolates showed an outstanding activity at different concentrations (50, 100, 150 and 200 μg/ml). The MIC value for the PDR bacterial isolates ranged from 25-150 μg/ml and MBC value ranged from 50-300 μg/ml. ZnO2-NPs have exhibited efficiency as an active antibacterial agent against PDR pathogens suggesting that the ZnO2-NPs are potentially valued for food safety applications.

Keywords: Foodborne diseases, Zoonotic pathogens, Antibiotics, Multidrug-resistant, Pan drug resistant, Metal oxides nanoparticles.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia