A CASE STUDY ON BULLOUS SYSTEMIC LUPUS ERYTHEMATOSUS
Binu K. M.*, Jincy Mary Alex, H. Doddayya and S. S. Antin
Bullous systemic lupus erythematosus (BSLE) is a rare autoimmune blistering disorder that typically manifests as an acute vesiculobullous eruption in a patient with known systemic lupus erythematosus (SLE). Rarely, BSLE is the initial clinical manifestation of SLE. characterized clinically by tense bullae involving photo-exposed areas and histologically by subepidermal bullae with predominantly neutrophilic infiltrate and immunoglobulin (IgG, IgA, and IgM) and C3 deposition at the dermo-epidermal junction indirect immunoflurosence. Approximately 76% of patients with SLE will have skin changes at some stage during the course of their disease. Aggressive treatment with Immunosuppresents and use of analgesics, corticosteroids, Hydroxychloroquine can cure the disease up to certain extent. Awareness of clinicians regarding diagnosis and accurate treatment can reduce the disease burden.
Keywords: Bullous systemic lupus erythematosus, Autoimmune, Skin, Bullae, Immunoglobulin, Disease.
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