ASSESSMENT OF SERUM TESTOSTERONE LEVEL IN MALES WITH IDIOPATHIC ANTERIOR URETHRAL STRICTURE DISEASE AND ITS EFFECT ON STRICTURE SEVERITY

*Dr. Ravi Pandey, Dr. Dharmendra Jangid, Dr. Vinay Tomar and Dr. Sher Singh Yadav

ABSTRACT

Aim: To study the levels of testosterone in patients with idiopathic anterior uretheral strictures and its effect on the disease severity i.e. stricture length. Material and method: The present study was conducted in the department of Urology, among 100 cases of anterior urethral strictures. Subjects were further categorised into group A and B i.e. 50 with idiopathic anterior urethral stricture were assigned as Group A and 50 with known cause of anterior urethral strictures were assigned as Group B respectively. Detailed history, physical examination and relevant investigations like UFM, RGU-MCU done. We defined low serum testosterone when total testosterone level was <300 ng/dl. Stricture characteristics, such as location and length, were obtained from operative reports. Datawas analyzed using IBM SPSS. Statistics Windows, Version 22.0. Results: Etiology reported in case group was idiopathic whereas in control group the most common etiology was traumatic. Mean testosterone level in case and control group was 288.70±117.21 and 390.08±159.41 respectively. Serum Testosterone and idiopathic anterior uretheral strictures length showed negative correlation. Conclusion: Low serum testosterone may be more prevalent in idiopathic anterior urethral stricture particularly in younger patients and does not show significant correlation with disease severity(stricture length).

Keywords: Testosterone level, stricture, etiology, idiopathic.