EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

TWO HOURS POSTPRANDIAL EFFECT OF COMMONLY USED SOFT DRINK (COKE) ON PLASMA GLUCOSE LEVEL IN NIGERIA

Agbesor Innocent Nwouzuke*, Zaccheaus Awortu Jeremiah and Bashir Hamza

ABSTRACT

Two hours postprandial effect of oral administration of soft drink (coke) was carried out on 111 apparently healthy students between the age 17-35 years in Rivers State University, Nkpolu, Port Harcourt. A total of 50 samples were collected from Females aged 21-30 years and 61 samples from Males aged 17-35 years. The results of the analysis in group A (one bottle of coke) showed mean fasting plasma glucose concentration of 4.0+0.255Mmol/l among females and 4.1+0.453Mmol/l among males. After oral administration of one bottle of coke, mean plasma concentration for both sexes increased to 4.1+0.315Mmol/l for females and 4.5+0.292 Mmol/l for males. Statistical evaluation of results showed significant difference in mean plasma fasting value and after oral administration of one bottle of coke (p< 0.05). In group B (two bottles of coke) subjects, mean fasting plasma glucose in females was 4.0+0.242Mmol/l and in males 4.2+0.382Mmol/l. After oral administration of two bottles of coke, the mean plasma glucose value for females increased to 4.6+0.251Mmol/l and males to 4.7+0.362Mmol/l. Statistical evaluation of results showed significant difference between mean plasma fasting value and value after oral administration of two bottles of coke (p<0.05). The oral glucose tolerance test (OGTT) graph for both taken one and two bottles of 350ml of coke did not return to the fasting level. Hence oral administration of one or two bottles of coke can enhance the development of postprandial hyperglycaemia in those subjects that are genetically predisposed to diabetes mellitus.

Keywords: Coke, 2-hours postprandial, OGTT, Hyperglycaemia, Diabetes Mellitus.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )