EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

ASSESSMENT OF RIGHT ATRIAL FUNCTION IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS WITH DIFFERENT PULMONARY ARTERY SYSTOLIC PRESSURE BY THREE-DIMENSIONAL ECHOCARDIOGRAPHY

Ying LI, *Hongyan CUI, Shengda SONG, Lihua SUN, Mengyao SUN, Bijun TAN and Guangsen LI

ABSTRACT

Objective: To evaluate the right atrial function in patients with systemic lupus erythematosus (SLE) complicated by estimated pulmonary arterial hypertension (PAH) by three-dimensional echocardiography(3DE). Methods: According to the severity of PAH estimated by echocardiography, a total of 102 SLE patients were partitioned into three groups, group A was SLE without PAH(n=37), group B was SLE with mild PAH(n=34), group C was SLE with moderate to severe PAH(n=31). Thirty healthy volunteers were selected into separate group as in contrast (group D). The active emptying volume index (AVEI), the total empty fraction index(EFI) and passive empty fraction index(EFIpas) were measured. Results: Group B and Group C have higher Right Atrial Active Emptying Volume Index (RAVIa) than the control group, and the RAVIa is positively correlated to the pulmonary artery systolic pressure (PASP) (all P<0.05). Group B and Group C have lower Right Atrial Volume Passive emptying fraction (RAVpEF)and Right Atrial Total Volume emptying fraction (RAVtEF) than the control group, exhibiting a negative correlation to PASP (P<0.05). The RAVaEF of Group B and Group C are higher than that of the control group (P<0.05). Conclusion: 3DE offered an accurately and effective method to evaluate the RA function in patients with SLE.

Keywords: Systemic lupus erythematosus, three-dimensional echocardiography, right atrial function, pulmonary hypertension.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )