EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

ANTIBACTERIAL ACTIVITY OF SOME MEDICINAL PLANTS AGAINST CAR-BAPENEM-RESISTANT ACINETOBACTER BAUMANNII ISOLATED FROM PATIENTS

Mohammed M. Matin*, Sreebash C. Bhattacharjee, Md. Shihabul Hoque and Forkan Ahamed

ABSTRACT

Carbapenem-resistant Acinetobacter baumannii has currently emerged as a major threat leaving behind no antibac-terial treatment options. Therefore, current research has been focused on finding out effective natural plants with antibacterial activity against these bacteria. Water, methanol, petroleum ether and ethanol extracts of Polygonum hydropiper L, Barringtonia acutangula L., Acacia nilotica L. and Abrus precatorious L. were tested against four carbapenem-resistant A. baumannii isolates (Ab1, Ab5, Ab9 and Ab13). Polygonum hydropiper L. extracts were found more effective although other extracts also showed some activity. Ethanol extract of Polygonum hydropiper L. showed highest activity with 17.83 mm zone of inhibition. Minimum inhibitory concentrations (MICs) of the extracts ranged from 7.81 g/mL to 15.63 g/mL and minimum bactericidal concentrations (MBCs) of the extract ranged from 31.25 g/mL to 62.50 g/mL against the four isolates. Ethanol extract of Polygonum hydropiper L. may be a potential source of antibacterial treatment against carbapenem-resistant Acinetobacter baumannii.

Keywords: Carbapenem Resistant, Acinetobacter Baumannii, Polygonum Hydropiper L, Antibacterial Activi-ty, MIC, MBC.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )