EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

PHENOTYPIC CHARACTERIZATION OF ACINETOBACTER FROM VARIOUS CLINICAL SAMPLES AND MOLECULAR STUDY ON IMIPENEM RESISTANT STRAINS IN A TERTIARY CARE HOSPITAL, ENATHUR, KANCHIPURAM.

*Dr. M. Anuradha, Dr. K. Muthulakshmi, Dr. Somasunder

ABSTRACT

Background: Acinetobacter is a Gram negative nosocomial pathogen, incapable of causing infection on its own, however causes colonization in susceptible patients especially with underlying pathology such as neutropenia or organ transplants or CAPD or catheter induced bacteruria. It is one of the causative agent of nosocomial pneumonia. A study is done on its causative role among various infections like UT infections, wound infections, respiratory tract infection, Blood stream infections, for a period of 1year duration. Antibiotic susceptibility Pattern studied and by using PCR technique imipenem bla OXA genes were studied. Materials and methods: Acinetobacter is identified by various Biochemical tests such as sugar fermaentation, indole test, methyl red, VP, Citrate utilization test, TSI, Urease test, mannitol motility. Further studied for Antibiotic susceptibility by using Muller – Hinton agar and Kirby bauer method and molecular characterization by PCR. Results: Among 1665 urine samples received over a period of 1 year duration 523 (31.41%) were culture positive, among culture positives commonest isolate was Escherichia coli 230(43.97%), citrobacter was least common being 6 out of 523 where as Acinetobacter were 16/523 (3.05%).Among pus samples 553 were total samples 409 were culture positive(73.96%),Staphylococcus aureus 173/409 (42.29%) was being the most commonest causative organism and Entercoccus was least common 4/409(0.997%), Acinetobacter were causative agents for 8/409(1.95%).Among sputum samples total nuber were 1313 and culure positive were 512 (38.99%). Acintobacter was isolated from 15 cases (nosocomial) 15/512(3%). Among various fluids there were 31 isolates among 137 sample (19/147) however, Acinetobacter was not isolated and among blood stream infections 3/386 cases(0.77%) were positive for acinetobacter. Conclusions: Among various samples Acinetobacter was causative agent for only few casaes of 1 – 3% however common among hospital acquired infections.2 strains were resistant to imipenam and 2 strains were moderaetly resistant to imipenam .The present study shows their greater incidence among women with age group (50-60). Imipenem resistant strains were studied for blaOXA genes.

Keywords: Acinetobacter, pathology, using PCR technique imipenem bla OXA genes.


[Full Text Article] [Download Certificate]

Citation

  All Since 2019
 Citation  3086  2560
 h-index  18  17
 i10-index  64  44

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 March 2024 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

  • EJPMR: MARCH ISSUE PUBLISHED

    MARCH 2024 issue has been successfully launched on MARCH 2024.

  • EJPMR New Impact Factor

    EJPMR Impact Factor has been Increased to 7.065 for Year 2024.

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia