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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



Christèle TCHOPBA NGUEPOU*, Gnatoulma KATAWA, Sika DOSSIM, Mounerou SALOU, Ahoefa A. VOVOR, Yaovi A. AMEYAPOH


Urinary tract infections can complicate the condition of sickle cell patients by kidney damage. This study was initiated to evaluate the prevalence of urinary tract infections bacteria carriage in sickle cell patients and to determine the antibiotics susceptibility profile of these bacteria. Homozygous sickle cell patients, "SS", in the steady state, followed at the “Centre Hospitalier Universitaire-Campus” (CHU-Campus) of Lomé, were recruited on the basis of precise criteria. For these patients, cytobacteriological examinations of urine (ECBU) were performed. In all, 129 sickle cell patients with "SS" phenotype aged between 3 and 52 years, mean age 18.33 ± 0.90 years were selected. The sex ratio M / F was 0.72. The prevalence of carriage of bacteria responsible for urinary tract infections was 9.30%, 12 subjects, 11 of which were female. Escherichia coli was the most isolated bacteria, accounting for 66.67% of the isolates. Furthermore 85.7% of E. coli strains were resistant to Sulfamethoxazole-Trimethoprim, 75% to Nalidixic Acid, Ticarcillin and Ticarcillin-Clavulanic Acid, 14.3% to Piperacillin-Tazobactam and 12.5% to Ertapenem. All E. coli strains were sensitive to Amikacin and Meropenem. The results of this study will contribute to better management of infections in sickle cell patients by screening for urinary tract infections and routine antibiotic susceptibility testing.

Keywords: Sickle cell anemia, urinary tract infections, asymptomatic bacteriuria, antibiotic susceptibility, Lomé.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia