EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

ASSESSMENT OF THE FORMATION OF IMMUNOLOGICAL DISTURBANCES IN MEN WITH AZOOSPERMIYA

*Fayzullaeva N. Ya., Musakhodjaeva D. A., Ruzibakieva M. R., Yarmukhamedov A. S., Nurmukhamedov B. B., Azizova Z. Sh. and Djumaeva D. N.

ABSTRACT

A study was conducted to study the state of the immune system in 132 men with primary infertility. It was revealed that this contingent had an imbalance in the content of some parameters of the immune system. Thus, the level of CD3 + - and CD4 + lymphocytes was reduced, the killer activity was increased. The content of CD20 + lymphocytes and the concentration of IgG and IgA were elevated. The level of pro-inflammatory cytokines (IL-2, IL-6, TNFα) in the examined patients was elevated. The results indicate the important pathogenetic role of the immune mechanisms in men with primary infertility.

Keywords: Male infertility, immunity, cytokines.

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