EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

ANTI HYPERLIPIDEMIC ACTIVITY OF SIDDHA DRUG KARIVEPPILAI CHOORANAM IN HYPERLIPIDEMIC INDUCED WISTAR ALBINO RAT MODELS

Manoharan A.* and Chittibabu C. V.

ABSTRACT

Hyperlipidemia is a major risk factor in Cardio Vascular and Central nervous systems. Hyperchloestredemia is a most important condition involving in abnormal levels of lipids (or) composition of circulatory plasma levels. Recent studies have been reported that hyperlipidemia is present in 25-30% of urban and 15-20% rural area subjects (Rajveev Gupta et al. 2017). In India few larger studies have reported of different form of lipid abnormalities (ICMR INDIA B STUDY 2011, 2014 and PURE study (Camacho PA 2019). Aim: The present study was carried out to determine the anti hyperlipidemic activity of Kariveppilaichoornam. Material and Methods: Anti hyperlipidemic activity assay was performed by high fat diet induced Wister albino rat models, atrovastitin was used as the reference standard respectively. Stastical Analysis Used: All the experiments were performed the values are expressed as Mean ± SEM. Values were find out by using ONE WAY ANOVA followed by Newman Keul’s multiple range tests. Values were significantly different from normal control at P< 0.01. Values were significantly different from hyperlidemic control at P< 0.01. P values <0.05 were considered as statistically significant. Results: End of study shows KVC 100 to 200 mg dosage was reduced in lipid level, especialy in total cholesterol and triglycerides. Conclusion: The KVC has significant hypolipidemic effects on HFD diet induced Wister albino rats.

Keywords: Hyperlipidemia, Dyslipidemia, Obesity, Kariveppillai Choornam.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )