EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

RNA-NANOPARTICAL IN CANCER THERAPY: PROGRESS AND CHALLENGES

Abhishek Jain*, Sanjay Sharma, Shirish Deshpande, Pritam Jain, Mahesh Kamalja

ABSTRACT

Currently a popular era in Nano medicine is the implementation of RNA nanoparticles for cancer diagnosis. RNA interference (RNAi) is after-transcriptional gene regulating mechanism where Coding, non-coding takes place. This technology is powerful technology to diagnose and treat diseases. The article endeavors to highlight to clarification of the mechanism of siRNA with concern to possible applications which are established on cancer therapy, and to discuss the possible effectiveness of nanoparticle on the basis of delivery system. Self-assembled nanoparticle (NP) is developed and it competently delivers to small interfering RNA (siRNA) by intravenously to the tumor. The nanoparticle was found by mixing with siRNA, carrier, DNA, and lipids, preceded by after-change. Newly FDA appreciation of the first polymer drug and additional ones in the clinical linked RNA polymer has to be highly therapeutic and diagnostic value. It has been established to be a particular useful means for cell-type definite delivery of other RNA therapeutics like siRNA. While RNAi has helped speed up the discovery and understanding functions of gene, it also has great potential as a therapeutic and potentially prophylactic modality. This article stated about the development in the RNA polymer and also provides some examples of their diagnostic applications and therapeutics.

Keywords: SiRNA Nanoparticle, Cancer therapy & Treatment, RNA, Drug Delivery.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia