EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

EFFECT OF 3,4-METHYLENEDIOXYMETHAMPHETAMINE ON MALE FERTILITY HORMONE AMONG SUDANESE YOUTH USERS IN KHARTOUM STATE

Nosiba Khalid Gamer Aldrin, Alneil M. Hamza and Abdalla E. Ali*

ABSTRACT

Background: Methamphetamine (Kharsha) stimulates the central nervous system and affects the body tissues and neurotransmitters like dopamine. That affected on male fertility hormones. The study aims to assess the effect of methamphetamine on the male fertility hormones FSH, LH, and Testosterone hormones level. Methods: Cross-sectional case-control study, carry out in Khartoum state in Sudanese youth Chronic Addiction to methamphetamine. Total of study group 100 participants, 70 case study and 30 as a control group, blood samples were collected measured for FSH, LH and testosterone hormones by Enzyme-linked immunosorbent assays Principle in the antigen-antibody reaction. Results: Decrease the level of FSH (3.39±1.45) P-value=0.001 and testosterone (3.36±2.65) P-value=0.035 within normal range among case study, and increase LH (11.94±4.60) P-value=0.001 comparing with the control group. Conclusion: The study concludes that the chronic addiction of methamphetamine may cause variable effects on male fertility hormone levels, it may lead to infertility.

Keywords: 3,4-methylenedioxymethamphetamine, FSH, LH and Testosterone hormones.

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