( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Nkechi Obiofu Ezenobi*, Hanson Ige Ogbu, Dumle Tina Kpea


The undesirable presence of certain types of microbes and their metabolites in pharmaceutical products like syrups are increasingly becoming a matter of public health concern. The issues involved are not just localized but have become global because of the consequences of treating patients with contaminated products. Patients may have secondary infection from pathogenic organisms, which can complicate treatment procedures especially for those with compromised immunity or whose immune systems are not well developed. The study was designed to test the susceptibility of pathogens isolated from cough syrups sold in Port Harcourt metropolis, south-south Nigeria. A total of fifty cough syrups were randomly purchased from approved pharmacy outlets and subjected to microbiological assessment. Other test performed were pH, stability, resistance-susceptibility on the isolates using standard procedures. The result indicated that 70 % of the cough syrup were not contaminated while 30 % were contaminated and the microbial load above the acceptable limits (<102 and <101 CFU/mL for bacteria and fungi respectively) as specified by USP. The major contaminants were Staphylococcus aureus, (35.29 %), Pseudomonas aeruginosa (29.43 %), Escherichia coli (11.76 %), Candida albicans (11.76 %), Klebsiella pneumoniae (5.88 %) and Proteus species (5.88 %). The pH value ranged from 2.76 to 7.40 with 96 % of the being acidic. For stability, 4 out of 50 samples failed the test. Susceptibility results showed that the isolates had single and multiple drug resistant patterns to the antibiotics used. The presence of potentially pathogenic microorganisms poses serious health concern, hence the need for a routine microbiological assessment to encourage good manufacturing practice.

Keywords: Antimicrobial, Susceptibility, Contamination, Pathogens, Paediatrics, Cough syrup.

[Full Text Article]



  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 September 2023 Issue has been Published, Kindly check it on


    SEPTEMBER issue has been successfully launched on 1 SEPTEMBER 2023.

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    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database