EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

COMPARISON BETWEEN IMMUNOCHROMATOGRAPHIC CARD TEST AND WIDAL TEST IN PROVISIONALLY DIAGNOSED CASES OF ENTERIC FEVER

Chaudhary Devendra, Umar Farooq* and Vasundhara Sharma

ABSTRACT

Introduction: Typhoid fever is a life threatening systemic infection occurring in less developed areas of the world and continues to be a major public health problem. It is a serious bacterial infection of the intestinal tract and sometime in the blood stream caused by bacterium Salmonella typhi. Aims: To confirm provisionally diagnosed cases of enteric fever by immunochromatographic card test (typhi-dot test) and widal test. Materials and Methods: 100 patients were included in his study. The comparative study of rapid card test and widal test in the diagnosis of enteric fever was conducted for a time period from January 2018 to october 2018 in the department of microbiology Teerthanker Mahaveer Medical College and Research Centre. Results: Among 100 patients with suspected case of Typhoid fever were studied. All patients who fulfilled the inclusion criteria immediately undergone for widal and Typhidot test. Out of 100 patients 31 (31%) were males and 69 (69%) were females. Out of 31 male cases Widal test was positive in 12 (38.70%) cases whereas 19 (61.29%) were negative, and in 69 females widal test was positive in 20 (28.98%) cases whereas 49 (71.01%) were negative. Out of total 31 male cases typhidot was positive in 19 (61.29%) cases whereas 12 (38.70%) cases were negative, and in 69 females typhidot was positive in 29 (42.02%) whereas 40 (57.97%) were negative. Conclusion: After analyzing the findings of the present study it was concluded that although Typhidot (rapid Diagnostic test) test is highly sensitive and specific test in diagnosing of enteric fever compare to widal test. Typhidot test is a rapid easy to perform more reliable test for enteric fever as compared to widal test and can be useful in early Institution of therapy. However in large prospective study would be required to fully evaluate the usefulness of this test in countries endemic to enteric fever.

Keywords: Typhidot, widal test.

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