PLATELET RICH FIBRIN (PRF) AND ITS ROLE AS HEALING AID IN IMPLANT DENTISTRY
Aim: The aim is to review and discuss the strategies available for use of platelet rich fibrin (PRF) as healing aid in implant dentistry. This review article is also to sum up different types of platelet concentrates, classification, architecture, protocol and there salient features. Background: Platelet rich fibrin (PRF) is a fibrin matrix during which platelet cytokines, growth factors, and cells are trapped and may be released after a certain time which can serve as a resorbable membrane, Faster wound healing has always been a challenge for clinicians since ages. Choukroun et al (2001) were amongst the pioneers for using PRF protocol in oral and maxillofacial surgery to improve bone healing in implant dentistry, Autologous PRF is taken into account to be a healing biomaterial and presently, studies have shown its application in numerous disciplines of dentistry. Wound healing is a complex biological process where many cellular events taking place simultaneously leading to the repair or regeneration of damaged tissues. Blood platelets are the first cells to respond to wound healing. The ability of blood platelets to secret growth factors makes them the foremost requirement in wound healing. The aim of this review article is to sum up different types of platelet concentrates, classification, architecture, protocol and there salient features. Materials and Methods: By using specific keywords, electronic search of scientific papers was carried out on the whole PubMed database with custom range of five years. The electronic search yielded 203 papers; based on inclusion and exclusion criteria which were specifically predetermined, 63 papers were identified as suitable to the inclusion criteria and the remaining 140 papers were excluded. After adding one selected papers through hand search, full text of all the articles retrieved and review was done. By pooling the extracted data from chosen papers, the reviewed data was synthesized. Conclusion: Recently by showing good promising results with use of the plasma rich fibrin (PRF), it has proved to have a good prospect for its use as healing aid in various aspects of the implant dentistry.
Keywords: Plasma rich fibrin (PRF), platelet rich plasma (PRP), wound healing.
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