ANTIOXIDANT AND HEPATOPROTECTIVE EFFECT OF BLACK GINSENG ON THE IMPROVEMENT OF FEMALE GYNECOLOGIC PERIOD
Un Kyu Park, Yong Lim, Ji Hye Oh, Man Kyu Huh* and Seock-Yeon Hwang*
This study was conducted to investigate the effect of black ginseng on the improvement of female gynecologic period using black ginseng. The body weight of the black ginseng composition was significantly decreased compared to the control group at 5 and 7 weeks in the experimental group, but the density of estrogen was no significant difference in both groups. Major biochemical indicators, calcium and phosphorus were significantly decreased in the ovariectomized group. Total cholesterol, LDL cholesterol and triglyceride were significantly increased by ovariectomy compared with normal controls. Total cholesterol and high density and low density lipoprotein cholesterol were significantly decreased in the group treated with the black ginseng composition. In alanine transaminase (ALT), aspartate transaminase (AST), the main indicators of liver function were significantly increased in the ovariectomized group. Compared with the normal control group, the groups treated with the black ginseng composition and the control group showed significant increases and decreased in the ovariectomized group in superoxide dismutase (SOD) and catalase (CAT), Glutathione-S-transferase (GST), glutathione (GSH) and malondialdehyde (MDA). In both the males and females, fidelity and decreased status of T cells and B cells were observed in the splenic zone.
Keywords: Black ginseng, liver function, ovariectomy, superoxide dismutase.
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