NADPH OXIDASE 4 (NOX4) AND CANCER
Kamar Hasan Ansari* and Fan Yue Zu
The essay reviews the expression of NADPH oxidase (NOX4). It looks into how facilitates the generation of ROS and the physical and chemical properties of NOX4 relates with ROS. NOX4 plays a vital role in various types of cancers including lung cancer, colorectal cancer, breast cancer, hepatocellular cancer, and endometriosis ovarian cancer. Lastly, the essay discussed the expressions of NOX4 in many cancers and its significance.
Keywords: NOX 4; NADPH; ROS; Tumorigenesis; Angiogenesis; Cancer.
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