EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

YELLOW FEVER VIRUS (YFV) INFECTION EVALUATION USING RAPID DIAGNOSTIC TESTS (RDTS) BASED ON ANTI-YFV IGM/IGG

Yong-Gyoo Lee, Man Kyu Huh and Yong Lim*

ABSTRACT

Yellow fever (YF) is an acute viral haemorrhagic disease transmitted by infected genus Aedes mosquitoes. The yellow fever virus (YFV) is mostly found in tropical and subtropical areas of Africa and South America. Outbreaks recently reached considerable proportions in terms of spatial distribution and total numbers of cases, with multiple exports, including to China. There is no medicine to treat or cure infection. Rapid diagnostic tests (RDTs) for the detection of YFV antigens are based on the immunochromatographic test principle. A total of 124 prospective serum samples submitted for yellow fever virus (YFV) IgM and IgG testing. All 124 serum samples among 124 in Brazil showed IgG positive results with YFV. Thus sensitivity of the GenBody Company RDT was 100.0% for IgG. 11 samples among 12 were negative. Specificity of GenBody kits was 91.6% (11/12) for YFV. It is suggested that the rapid diagnosis kit of GenBody -company can be used as a useful test for Yellow fever virus management.

Keywords: Yellow fever virus (YFV), IgG, IgM, rapid diagnostic tests (RDTs), RT-PCR of YFV.

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