PREVALENCE OF AMELOBLASTOMA AND ITS CLINICAL AND HISTOPATHOLOGICAL FEATURES: A RETROSPECTIVE

Dr. Humaira Nazir and Dr. Ifzah Usman*

ABSTRACT

Introduction: Prevalence of ameloblastoma has been established worldwide but collective data of ameloblastoma in Southeast Asian countries has not been well analyzed. Aim: To report prevalence and clinical features of ameloblastoma and its histopathological variants in Tumur city, Karnataka. Materials and Methods: A retrospective study on ameloblastoma was performed based on the oral biopsy specimens available in the Department of Oral Pathology, Sri Siddhartha Dental College and Hospital Tumkur city, Bangalore. The data collected from March 2004 to May 2014 was subjected to statistical analyses with the SPSS version 17.0 using Pearson’s chi square (χ2) test and t-test. The critical level of significance was set at p<0.05. Results: Total of 400 cases were reviewed, 23 cases (17.3%) were diagnosed with ameloblastoma. The mean age of the patients was 25.3±13.6 years. The predominance was observed in the mandible (92.7%). Posterior body-ramus-angle region was the most common site. Almost all cases were asyptomatic and most common clinical manifestation was swelling of affected region. Multilocular radiolucency was observed in 60% of cases, whereas 40% were unilocular. Three subtypes of ameloblastomas were diagnosed: unicystic ameloblastoma (23%), conventional solid/multicystic ameloblastoma (68%), and desmoplastic ameloblastoma (9%). The most common histologic pattern was the plexiform type followed by follicular type. Conclusion: Prevalence of ameloblastoma in tumkur populations correspond with data from geographic areas of other Asian countries.

Keywords: Mandible, Multilocular, Plexiform, Southeast Asia.