( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Mamit Kumar*, Jyoti Memoalia, Megha Gupta, Geetinderpreet Kaur and Amit Kumar


Aim: The aim of this study is comparative analysis of post-operative analgesic requirement in patient undergoing minor oral surgery using 2% Lignocaine with 1:200000 Adrenaline and Buprenorphine versus 2% lignocaine with 1:200000 Adrenaline. Materials and Method: One hundred and four patients requiring minor oral surgery were included in the study. 1 ml of Buprenorphine Hydrochloride injection I.V which contains an equivalent of 0.3 mg Buprenorphine was withdrawn into a syringe and injected into a 30 ml vial of 2 % Lignocaine with Adrenaline 1:200000. Thus each ml of local anaesthetic contained 0.01 mg of Buprenorphine. This solution was labelled and used for the study. Results: The duration of analgesia in Group I and II was found to be 36.02 ± 1.5 h and 13.39±1.4 h. The average consumption of NSAIDs was found to be 1.42 as compared to Group II mean value of 2.32 (P < 0.0001). Conclusion: The results of the present study showed that addition of small amounts of buprenorphine to 30 ml lignocaine with adrenaline 1:200000 for minor oral surgery results in significant improvement in postoperative analgesia up to 36 h and markedly reduce the need for excessive analgesic intake. Thus reducing the adverse effects associated with excessive use of NSAIDs.

Keywords: Adrenaline, Buprenorphine, Hydrochloride, Analgesia.

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )