A STUDY ON EFFICACY OF ALPINIA GALANGA AGAINST CHEMICAL INDUCED KIDNEY DAMAGE IN WISTAR ALBINO RATS
P. M. Vasanth*, P. Ramya, P. V. Prasad, V. Sarath Babu and K. Thyagaraju
ABSTRACT
The present study throws light on the effect of the plant Alpinia galanga (L.) in reducing the nephrotoxic effect that has been induced by potassium dichromate as well as gentamicin. The results of phytochemical screening components of ethanolic and aqueous extracts of Alpinia galanga (L.) leaves might be accountable for the effective antioxidant capacity like Thiobarbituric acid reactive substance(TBARS), Super oxide dismutase(SOD), Catalase(CAT), Reduced glutathione(GSH), and to estimated the effect of Alpinia galanga on different oxidative stress parameters in Kidneys. Effect of hydroalcoholic extract of Alpinia galanga (L.) leaves on gentamicin induced nephrotoxicity is analysed by the Creatinine (mg/dl), Urea (mg/dl), Blood Urea Nitrogen (mg/dl), Total protein (g/dl) levels.
Keywords: Plant Alpinia galanga (L.), oxidative stress parameters in Kidneys, Antioxidants.
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