SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF DEMECLOCYCLINE, DOXYCYCLINE AND HOSTACYCLINE
Dr. Y. Sivchandra*, Dr. T. R. Kishore and Dr. V. Suryanarayana Rao
New, rapid and sensitive spectrophotometric methods have been developed for the determination of Demeclocycline(DMC), Doxycycline(DC) and Hostacycline(HTC). The procedure is based on the observation that, DMC, DC and HTC forms coloured complex with vanadium(V), the absorbance of which is proportional to the amount of drug present. The variable affecting development of the colour have been investigated and the conditions are optimized.
Keywords: Spectrophotometric determination, Demeclocycline, Doxycycline and Hostacycline, vanadium(V).
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