MODERN DIAGNOSIS AND TREATMENT OF UTERINE SARCOMAS (LITERATURE REVIEW)

Mehriniso R. Oripova* and Mirdjalol D. Djuraev

ABSTRACT

Uterine sarcomas (US) are rare malignant tumors of mesenchymal origin. According to statistics, 8 cases of uterine sarcoma are detected annually in the world for 1 million women. The diversity of US, both in morphological structure and clinical features complicates the early and differentiated diagnosis, treatment and prognosis of this pathology. The risk of US after radiation therapy consist by 0,03-0,8%. Uterine fibroids are considered to be an independent risk factor for developing sarcomas in pre - and postmenopausal period. Currently existing methods allow to establish a diagnosis before surgery in only a 1/3 of patients. High malignancy of US, fast progression of the tumor, the tendency to frequent occurrence of local relapses, indicate the need for radical surgery. Timely radiation therapy improves long-term results of treatment.

Keywords: Mesenchymal tumors, leiomyosarcoma, endometrial stromal sarcoma, carcinosarcoma, uterine fibroids, uterine extirpation.