EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EVALUATION OF PHYTOCHEMICALS, ANTIOXIDANT POTENTIAL AND ANTIBACTERIAL ACTIVITY OF SIDDHA VEPPAMPATTAI THAILAM PRESCRIBED TO CURE WOUND, KANYAKUMARI DISTRICT - INDIA

R. Mary Suja* and B. Christudhas Williams

ABSTRACT

The main objective of the present investigation is to evaluate the phytochemical constituents, antioxidant potential and antibacterial activity of Siddha wound medicine prescribed by the Traditional Siddha Practitioner of Kanyakumari District, India. Veppampattai Thailam is an internal form of wound medicine. Phytochemical analysis of the Thailam, aqueous, ethanol and chloroform extract revealed the presence of alkaloid, saponin, reducing sugar and tannin constituents. The unexplored area of hydroxyl radical scavenging assay of Veppampattai Thailam and extracts varied from the minimum inhibition 48.57% (25μl) of aqueous extract to the maximum inhibition 84.21 % (100μl) of Ascorbic acid. On the otherhand, reducing power activity of the Thailam and extracts varied from the minimum inhibition 35.53 % (25μl) of aqueous extract to the maximum inhibition 86.79 % (100μl) of Vitamin C. The antioxidant assay of the Veppampattai Thailam and extracts indicated promising antioxidant activities in concentration dependent manner. The antibacterial activity of Siddha medicine prescribed for wound (Thailam) showed both positive and negative activity. The prescribed Veppampathi Thailam showed the maximum zone of inhibition (26 ± 0.001 mm) against Pseudomonas aeruginosa and minimum zone of inhibition (1 ± 0.213 mm) against Klebsiella pneumonia. On the other hand, ethanolic extract of the Thailam fail to inhibit the growth of Klebsiella pneumonia. The trial Siddha medicine highlights the effect of Veppampattai Thailam as a great potential source to rid wounds.

Keywords: Veppampattai Thailam, phytochemical, antioxidant, Kalanchi.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database