ACCOMPANYING IMMUNOPHARMACOTHERAPY IN PATIENTS WITH OVARIAN CANCER USING CYCLOFERON AND TACTIVIN
*Kamishov S. V. and Tillyashaykhov M. N.
An imbalance in the cytokine: IFN-γ / IL-6 ratios was studied. In norm IFN-γ / IL-6 - 1,2. In the group of patients with OC before treatment: IFN-γ / IL-6 - 0.5; in the group of patients after PCT without the use of immunotherapy - IFN-γ / IL-6 - 0.24; in the group of patients with EIPHT + cycloferon - 1.1, and in the group of patients with EIPHT + tactvin - IFN-γ / IL-6 - 0.9. Thus, in groups of patients with EIPHT and immunotropic drugs, there is a positive trend in the state of the immune system, which is reflected in the immunomodulating effect of IFN-γ and a decrease in IL-6. Apparently the use of immunotherapy in a combination of chemotherapy in our opinion is a justified and effective method that leads to the normalization of immunological parameters of the immune system, improves the immediate results of treatment, leads to a decrease in the intoxication of the disease, leads to a decrease in clinical manifestations of the disease.
Keywords: Cytokines, ovarian cancer, immunopharmacotherapy, polychemotherapy, interferon inducers, thymic preparations.
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