EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

PHYTOCHEMICAL STUDY AND EVALUATION OF ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF VITEX DONIANA SWEET (VERBENACEAE)

Ouattara Karamoko, Ouattara Lacinan*, Ouattara Abou, Rajib Majumder, Debopam Banerjee, Palashpriya Das and Suman Khowala

ABSTRACT

Owing to difficulties encountered in the use of synthetic antioxidants, research is moving more and more towards natural antioxidants particularly those from plants. It is in this context that we were interested Vitex doniana Sweet, a plant commonly used in the Ivorian pharmacopoeia for the treatment of several diseases. After an experimental study on a phytochemical screening of the methanolic extract of the plant, a quantitative estimate of total polyphenols (by the Folin-Ciocalteu method) and total flavonoids (by the method aluminum trichloride) was performed. Then; the antioxidant activity of the extract was evaluated through three methods: the method of DPPH (2.2 diphenyl picrylhydrazyl 1), the FTC (ferric thiocyanate) method and TBARS (thiobarbituric acid) method. The results obtained are shown the presence of various compounds including polyphenols groups. Furthermore, inhibition of DPPH radical coupled to the inhibition of lipid peroxidation by test FTC and the TBARS showed significant antioxidant activity for this extracted with a percent inhibition of 53% recorded by FTC and 52% by TBARS. The antioxidant activity of the observed plant would be partly due to its abundance of polyphenols.

Keywords: Vitex doniana, methanolic extract, phytochemical screening, antioxidant activity, Côte d’Ivoire.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia